EJNMMI Research

Table 1 Summary of contingency table statistics for scan parameters

From: Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment response

										No. that met criteria (n = 96)
Parameter	P value	Relative risk	95% CI	Sens	Spec	PPV	NPV	AUC	Criteria	Cured	Fail	Recur
TGAI change M6	< 0.0001	6.97	2.53–19.22	0.80	0.75	0.46	0.94	0.80	< 80%	19	7	9
TGAIcom change M6	< 0.0001	6.67	2.42–18.40	0.80	0.74	0.44	0.93	0.80	80%	20	7	9
Cavity M6	< 0.001	4.36	2.09–9.12	0.55	0.86	0.52	0.88	0.65	> 7 ml	10	7	4
Cav change M6	< 0.01	4.30	1.91–9.64	0.65	0.79	0.45	0.90	0.68	< 60%	16	6	7
M6 TGAI_com	< 0.001	4.05	1.98–8.32	0.50	0.88	0.52	0.87	0.68	> 1000	9	6	4
TGAI M6	< 0.001	4.05	1.98–8.33	0.50	0.88	0.53	0.87	0.69	> 600	9	6	4
Cavwall M6	0.00	3.95	1.90–7.90	0.50	0.88	0.53	0.87	0.70	≥ 3 mm	9	6	4
Mixed response M6	0.02	2.86	1.30–6.31	0.60	0.72	0.36	0.87	N/A	Intensified	21	8	4
V_total M6	0.05	2.20	1.03–4.56	0.45	0.77	0.35	0.84	0.64	> 7%	17	6	3
SUVmax M6	0.19	1.82	0.85–3.85	0.50	0.68	0.29	0.84	0.60	> 4	24	6	4
Cav change M1	0.01	2.80	1.33–5.92	0.50	0.80	0.40	0.86	0.52	< 33%	15	5	5
Cavity M1	0.04	2.50	1.18–5.32	0.35	0.87	0.41	0.84	0.57	> 20 mm³	10	6	1
TGAI change M1	0.07	2.24	1.05–4.78	0.40	0.82	0.36	0.84	0.67	< 5%	14	4	4
TGAI_com change M1	0.16	1.80	0.83–3.89	0.40	0.76	0.31	0.83	0.66	15%	18	3	5
V_total change M6	0.01	2.89	1.39–5.77	0.40	0.87	0.44	0.85	0.66	< 50%	10	5	3
Cavity Dx	0.18	1.72	0.79–3.71	0.45	0.72	0.29	0.83	0.53	> 16.5 ml	22	6	3

Ranked according to relative risk of unfavourable outcome. Fisher exact test was performed to determine significance. Sens (sensitivity), spec (specificity), PPV (positive predictive value), NPV negative predictive value. Change (change from baseline), intensified (at least one intensified or new lesion), month 6 (M6), percentage change from baseline to M6 (change), total glycolytic activity index (TGAI), composite TGAI (TGAI_com), cavity wall thickness (Cavwall), total abnormal density volume (V_total)

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