Skip to main content

Table 2 Anatomical distribution of sarcoidosis lesions on FLT- and FDG-PET (N = 14)

From: FLT-PET for the assessment of systemic sarcoidosis including cardiac and CNS involvement: a prospective study with comparison to FDG-PET

Anatomical site

FLT-PET

FDG-PET

p value

Agreement

Lymph nodes

    

Thoracic

10/14 (71%)

10/14 (71%)

0.99

0.65 (95% CI 0.21 to 1.0)

Cervical

7/14 (50%)

8/14 (57%)

0.72

0.29 (95% CI − 0.21 to 0.78)

Abdominal/pelvic

1/14 (7.1%)

5/14 (36%)

0.077

0.32 (95% CI − 0.18 to 0.81)

Heart

    

Left ventricle

6/14 (43%)

7/14 (50%)

0.72

0.86 (95% CI 0.59 to 1.0)

Right ventricle

2/14 (14%)

4/14 (29%)

0.38

0.59 (95% CI 0.11 to 1.0)

Central nervous system

    

Intracranial

1/14 (7.1%)

0/14 (7.1%)

0.33

0.0 (95% CI 0.0 to 0.0)

Spinal/paraspinal

1/14 (7.1%)

1/14 (7.1%)

0.99

1.0 (95% CI 1.0 to 1.0)

Lung parenchyma

    

5/14 (36%)

5/14 (36%)

0.99

0.69 (95% CI 0.29 to 1.0)

Salivary glands

    

0/14 (0%)

1/14 (7.1%)

0.33

 − 0.11 (95% CI − 0.26 to 0.04)

Spleen

    

0/14 (0%)

1/14 (7.1%)

0.33

0.0 (–)

Liver

    

0/14 (0%)

0/14 (0%)

Bone

    

0/14 (0%)

0/14 (0%)

Average number of sites/per subject with active disease

    

1.6 (1.0)

1.8 (1.3)

0.75

0.78 (95% 0.45 to 0.93)

  1. FLT-PET = 3′-deoxy-3′-[18F]fluorothymidine positron emission tomography, FDG-PET = 2-deoxy-2-[18F]fluoro-d-glucose positron emission tomography
  2. Agreement between categorical and continuous variables was assessed using Cohen’s kappa and the intraclass correlation coefficient, respectively