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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: 18F-C2Am: a targeted imaging agent for detecting tumor cell death in vivo using positron emission tomography

Fig. 1

Radiochemical labeling of C2Am, using N-(5-[18F]fluoropentyl) maleimide, to yield 18F-C2Am. The rapid Michael addition reaction takes place under mild conditions (20 °C, pH5, HBS buffer) in the presence of ascorbic acid. The secondary structure of C2Am is shown, highlighting the single cysteine residue (top, yellow) and the active site (lower) containing three calcium ions (yellow spheres)

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