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Table 4 Discrepant cases with individual observer and consensus 2-h T:BP scores (positive ≥ 2.32). PD-L1 tumour proportion score (TPS) ≥ 1% considered positive by immunohistochemistry (IHC)

From: Inter- and intraobserver agreement of the quantitative assessment of [99mTc]-labelled anti-programmed death-ligand 1 (PD-L1) SPECT/CT in non-small cell lung cancer

Patient no. PD-L1 expression by IHC Observer A Observer B Observer C Consensus
TPS (%) PD-L1
Assessment
T:BP PD-L1
Assessment
T:BP PD-L1
Assessment
T:BP PD-L1
Assessment
T:BP PD-L1
Assessment
Concordance with IHC
6 3 + 1.39 1.79 2.18 < 2.32 Discordant
9 1 + 1.93 2.00 1.97 < 2.32 Discordant
11 2 + 2.06 2.37 + 1.99 < 2.32 Discordant
14 10 + 1.74 1.98 1.57 < 2.32 Discordant
16 2 + 2.21 2.47 + 2.77 + ≥ 2.32 + Concordant
17 65 + 2.29 2.70 + 3.10 + ≥ 2.32 + Concordant
20 0 2.19 3.56 + 2.19 < 2.32 Concordant
21 0 3.41 + 6.69 + 4.27 + ≥ 2.32 + Discordant
  1. Positive ( +), negative (−)