SPECT | Observer A | Observer B | Observer C | ICC (95% CI) | ICC level of agreement |
---|---|---|---|---|---|
ROImax (mean ± SD) | ROImax (mean ± SD) | ROImax (mean ± SD) | |||
Malignant lesion(s) ROI | |||||
Primary lung tumour (T) | 548 ± 150 | 560 ± 154 | 568 ± 157 | 0.94 (0.90–0.97) | Good to excellent |
Lymph node metastasis (LN) | 459 ± 167 | 461 ± 167 | 448 ± 163 | 0.97 (0.95–0.98) | Excellent |
Healthy reference tissue | |||||
Blood pool (BP) | 260 ± 80 | 295 ± 80 | 270 ± 83 | 0.90 (0.84–0.94) | Good to excellent |
Lung (freehand) | 249 ± 146 | 310 ± 157 | 251 ± 88 | 0.84 (0.75–0.90) | Moderate to excellent |
Lung (AA) | 279 ± 113 | 279 ± 108 | 250 ± 94 | 0.89 (0.82–0.93) | Good to excellent |
Lung (C) | 307 ± 121 | 286 ± 129 | 288 ± 128 | 0.88 (0.81–0.93) | Good to excellent |
Liver (freehand) | 1121 ± 274 | 1262 ± 288 | 1194 ± 274 | 0.97 (0.95–0.98) | Excellent |
Liver (GOJ) | 1116 ± 264 | 1185 ± 270 | 1219 ± 283 | 0.95 (0.92–0.97) | Excellent |
ROImax ratio (mean ± SD) | ROImax ratio | ROImax ratio (mean ± SD) | ICC (95% CI) | ICC level of agreement | |
---|---|---|---|---|---|
(mean ± SD) | |||||
Ratios | |||||
T:BP | 2.29 ± 0.98 | 1.99 ± 0.67 | 2.20 ± 0.77 | 0.83 (0.73–0.90) | Moderate to good |
T:L (freehand) | 2.56 ± 1.18 | 2.01 ± 0.71 | 2.40 ± 0.86 | 0.79 (0.68–0.88) | Moderate to good |
T:L (AA) | 2.10 ± 0.75 | 2.17 ± 0.86 | 2.41 ± 0.90 | 0.85 (0.77–0.91) | Good to excellent |
T:L (C) | 1.92 ± 0.71 | 2.20 ± 0.92 | 2.18 ± 0.88 | 0.80 (0.69–0.88) | Moderate to good |
LN:BP | 1.86 ± 0.65 | 1.65 ± 0.51 | 1.76 ± 0.66 | 0.87 (0.81–0.92) | Good to excellent |