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EJNMMI Research

Table 2 Relative differences to the reference algorithm

From: Asphericity of tumor FDG uptake in non-small cell lung cancer: reproducibility and implications for harmonization in multicenter studies

 

Relative differences, % (median, IQR)

5 mm versus 7 mm

7 mm versus 7 mm

9 mm versus 7 mm

5 mm versus 5 mm

9 mm versus 9 mm

ASP

 TOF4/8

205 (108–314)

7.6 (3.1–18.0)

38.8 (25.1–55.7)

30.7 (22.7–42.7)

9.3 (3.7–29.7)

 TOF4/16

363 (187–603)

–

33.5 (23.2–58.9)

–

–

 PSF + TOF2/17

85.3 (35.8–162)

12.8 (6.3–26.9)

34.4 (21.8–56.9)

50.1 (36.4–73.5)

16.2 (4.5–34.1)

 Q.Clear

24.7 (15.4–51.4)

31.3 (11.2–43.7)

47.8 (26.2–63.9)

73.1 (54.1–85.1)

29.1 (9.1–44.6)

SUVmax

 TOF4/8

34.0 (25.7–41.3)

1.2 (0.6–2.0)

12.8 (10.2–17.2)

6.2 (3.8–10.4)

0.7 (0.4–2.0)

 TOF4/16

43.1 (35.4–53.9)

–

12.6 (9.9–16.4)

–

–

 PSF + TOF2/17

39.1 (28.6–46.2)

4.9 (1.9–7.2)

11.2 (7.5–13.9)

12.1 (3.3–20.7)

3.0 (1.6–5.1)

 Q.Clear

17.2 (11.9–28.1)

5.1 (2.4–10.6)

11.7 (5.5–21.4)

14.6 (9.5–27.4)

7.1 (2.2–11.2)

MTV

 TOF4/8

29.9 (21.4–39.8)

2.3 (1.4–4.4)

11.7 (6.6–22.0)

6.2 (3.9–15.9)

1.3 (0.6–2.8)

 TOF4/16

36.4 (24.9–50.7)

–

12.4 (6.4–22.4)

–

–

 PSF + TOF2/17

31.9 (24.2–39.4)

6.1 (3.1–12.7)

9.3 (5.3–17.3)

21.7 (8.4–41.3)

3.4 (1.5–7.3)

 Q.Clear

14.6 (7.6–20.7)

6.3 (3.1–13.2)

10.3 (4.0–17.2)

30.0 (13.2–83.7)

10.8 (5.9–16.3)

  1. Relative differences in % (with interquartile range; IQR) are given for each algorithm relative to the reference algorithm TOF4/16. Different pairs of reconstructed spatial resolution (FWHM) are compared. Missing values reflect pairs of identical datasets
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