Evaluation of image quality with four positron emitters and three preclinical PET/CT systems

EJNMMI Research

Table 9 Comparison of %RC and %SD values reported from previous multi-radionuclide studies

System	Radionuclide	Activity (MBq)	Acquisition time (min)	Algorithm	Iterations/updates	%RC 1 mm	%RC 2 mm	%RC 3 mm	%RC 4 mm	%RC 5 mm	%SD	References
ALBIRA II	¹⁸F	8	15	MLEM	25	N/A	0.31	0.60	0.76	0.79	6.4	[11]
ALBIRA II	⁶⁸Ga	8	15	MLEM	25	N/A	0.10	0.30	0.42	0.56	6.7
ARGUS	¹⁸F	3.7	20	FORE-2D OSEM	48	0.28	0.8^a	0.9^a	1.0^a	0.92	15.1	[12]
ARGUS	⁶⁸Ga	3.7	20.88	FORE-2D OSEM	48	0.17	0.3^a	0.4^a	0.5^a	0.72	17.0
Mediso nanoScan	¹⁸F	3.7	30	Tera-Tomo 3D	52	0.18	0.46	0.68	0.79	0.87	5.0^a	[13]
Mediso nanoScan	⁶⁸Ga	4.19	30	Tera-Tomo 3D	52	0.09	0.20	0.36	0.48	0.60	5.0^a
Inveon	¹⁸F	3.7	20	3D-OSEM MAP	2/18	0.2^a	0.4^a	0.7^a	0.8^a	1.0^a	2^a	[9]
	⁶⁸Ga	3.7	22.88	3D-OSEM MAP	2/18	0.1^a	0.2^a	0.4^a	0.7^a	0.6^a	3^a
	⁸⁹Zr	3.7	80.4	3D-OSEM MAP	2/18	0.2^a	0.4^a	0.6^a	0.8^a	0.9^a	2^a
Molecules	¹⁸F	4–8	20	3D-OSEM	100	0.3	0.79	0.85	1.01	0.97	N/A	[14]
	¹¹C	4–8	30	3D-OSEM	100	0.52	0.56	0.86	0.93	1.02	N/A
	⁶⁸Ga	4–8	20	3D-OSEM	100	0.11	0.35	0.46	0.56	0.57	N/A

MLEM maximum-likelihood expectation–maximization, FORE-2D OSEM Fourier rebinning followed by 2D ordered-subsets expectation-maximization, 3D-OSEM MAP 3D ordered-subsets expectation-maximization in combination with maximum a posteriori, 3D-OSEM 3D ordered-subsets expectation-maximization
^aValues have been derived from the reference Figures and are approximate, N/A = the value is not reported in the reference