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Table 3 Test–retest cohort: correlations between reference tissue methods with varying RRs and the gold standard: DVRPI_GMCB

From: [11C]PIB amyloid quantification: effect of reference region selection

Reference region DVRRLOGAN DVRSRTM SUVr40−60 SUVr60−90
GM Cerebellum     
  r 0.88 0.85 0.81 0.89
 Slope 0.85 0.85 1.04 1.12
 Intercept 0.14 0.18  − 0.03  − 0.10
Whole Cerebellum     
 r 0.85 0.81 0.77 0.84
 Slope 0.81 0.84 1.00 1.05
 Intercept 0.09 0.03  − 0.11  − 0.15
WM Brainstem /Pons     
 r 0.81 0.84 0.78 0.80
 Slope 0.73 0.62 0.81 0.91
 Intercept  − 0.07 0.04  − 0.24  − 0.30
Whole Brainstem
Subcortical
    
 r 0.81 0.83 0.79 0.80
 Slope 0.74 0.58 0.83 0.92
 Intercept  − 0.06 0.11  − 0.24  − 0.29
Eroded WM     
 r 0.83 0.86 0.82 0.86
 Slope 0.57 0.52 0.67 0.63
 Intercept 0.07 0.13  − 0.10  − 0.08
  1. Values are shown for each of the methods and correspond to the linear regression analysis