From: Brain SPECT perfusion and PET metabolism as discordant biomarkers in major depressive disorder
At PET day acquisition | At SPECT day acquisition | p value | |
---|---|---|---|
Demographic characteristics | |||
Age (years, mean ± SD) | 50.50 ± 16.3 | 50.06 ± 16.7 | 0.020 |
Education | 1.000 | ||
> 12 years | 5 | 5 | 1.000 |
≤ 12 years | 10 | 10 | |
Marital status | 1.000 | ||
Single | 13 | 13 | 1.000 |
Couple | 3 | 3 | |
Clinical characteristics | |||
Depression duration (months) | 136.44 ± 120 | 132.56 ± 121.48 | 0.023 |
Number of depressive episodes | 2.31 ± 1.9 | 2.31 ± 1.9 | 1.000 |
SCID severity | |||
Mild | 2 | 2 | 1.000 |
Moderate | 1 | 1 | 1.000 |
Severe | 13 | 13 | 1.000 |
Melancholic features | 6 | 6 | 1.000 |
Treatments | |||
SSRIs | 5 | 7 | 0.500 |
SNRIs | 6 | 5 | 0.300 |
Tricyclics | 2 | 2 | 1.000 |
MAOIs | 1 | 1 | 1.000 |
Pramipexole | 1 | 1 | 1.000 |
Antipsychotics, first generation | 1 | 1 | 1.000 |
Antipsychotics, second generation | 3 | 4 | 0.607 |
Mood stabilizers | 0 | 0 | 1.000 |
Others | 3 | 2 | 0.350 |