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Table 2 SULmax, SULmean, SULpeak for normal tissue and the prostate tumor (mean ± range). Next the absolute difference and the relative difference between scan 1 and scan 2. The within-subject coefficient of variation (wCV) in %, the coefficient of repeatability (RC), both in % as in absolute SUL values

From: Day-to-day variability of [68Ga]Ga-PSMA-11 accumulation in primary prostate cancer: effects on tracer uptake and visual interpretation

Organ

Metric

Average SUL

Difference in SUL scan 2–1

Relative difference (%)

wCV (%)

RC (SUL)

RC (%)

Parotid Gland

SULmax

15.1 ± 3.3 (10.1, 23.1)

0.5 ± 1.2 (− 1.4, 2.6)

4.1 ± 9.0 (− 9, 21)

11.3

2.3

17.0

SULmean

9.6 ± 1.9 (5.8,13.7)

0.2 ± 1.2 (− 1.9, 2.3)

3.9 ± 11.9 (− 15, 26)

8.4

2.3

23.4

Aortic arch

SULmax

1.8 ± 0.3 (1.0, 2.5)

0.0 ± 0.3 (− 0.6, 0.8)

 − 0.2 ± 18.6 (− 31, 38)

13.2

0.6

36.5

SULmean

0.9 ± 0.1 (0.5, 1.2)

0.0 ± 0.1 (− 0.3, 0.1)

0.2 ± 12.2 (− 29, 25)

9.6

0.2

26.6

Liver

SULmax

7.2 ± 1.5 (5.0, 9.6)

 − 0.5 ± 1.3 (− 5.5, 1.3)

 − 7.1 ± 15.8 (− 63, 21)

6.5

1.4

31.1

SULmean

3.7 ± 0.8 (2.3, 5.5)

0.3 ± 0.4 (− 1.1, 0.6)

 − 3.4 ± 9.2 (− 25, 13)

11.2

0.8

17.9

Kidney

SULmax

42.5 ± 6.9 (27.1, 56.7)

0.3 ± 4.5 (− 6.4, 9.4)

1.0 ± 11.3 (− 17, 29)

8.6

8.5

22.2

SULmean

19.5 ± 3.8 (11.6, 28.1)

 − 0.5 ± 2.4 (− 5.2, 3.4)

 − 2.4 ± 15.0 (− 25, 13)

8.0

4.7

23.9

A. Abdominalis

SULmax

1.9 ± 0.4 (1.2, 2.8)

0.0 ± 0.4 (− 0.6, 0.8)

2.6 ± 18.2 (− 28, 44)

12.9

0.7

35.6

SULmean

0.9 ± 0.2 (0.4, 1.1)

0.0 ± 0.1 (− 0.2, 0.3)

1.8 ± 14.3 (− 29, 35)

10.7

0.3

29.7

Bone

SULmax

1.5 ± 0.4 (0.9, 2.5)

0.1 ± 0.4 (− 0.7, 0.8)

3.1 ± 25.2 (− 48, 45)

17.8

0.8

49.4

SULmean

0.5 ± 0.2 (0.3, 0.9)

0.0 ± 0.1 (− 0.2, 0.1)

 − 6.0 ± 14.0 (− 33, 17)

10.0

0.2

27.7

Bladder

SULmax

12.5 ± 8.9 (3.3, 43.7)

 − 1.6 ± 8.9 (− 40.2, 12.4)

2.0 ± 58.1 (− 112, 113)

41.1

17.2

113.8

SULmean

7.7 ± 5.2 (1.9, 32.2)

 − 0.3 ± 6.4 (− 7.7, 22.6)

9.2 ± 62.6 (− 108, 128)

43.9

12.3

121.8

Prostate tumor

SULmax

10.7 ± 7.3 (3.1, 32.3)

 − 0.2 ± 1.1 (− 2.2, 2.5)

 − 0.5 ± 11.2 (− 18, 21)

7.9

2.2

21.9

SULpeak

6.2 ± 3.5 (2.6, 13.3)

0.0 ± 0.6 (− 1.2, 1.4)

1.2 ± 9.2 (− 15, 19)

6.5

1.1

18.1

TBR

SULmax

5.9 ± 4.2 (1.7, 17.8)

 − 0.2 ± 1.2 (− 3.3, 1.9)

 − 1.0 ± 19.7 (− 43, 42)

13.8

2.4

38.4

SULpeak

5.4 ± 1.3 (2.1, 12.5)

0.2 ± 0.6 (− 1.0, 2.4)

5.7 ± 17.1 (− 19.5, 27.6)

9.9

1.6

27.5

  1. Values are displayed as mean ± standard deviation (min, max). Average SUL of each site was calculated as mean over all subjects and all scans. Difference SUL and the relative difference are calculated as the group average of the difference