Table 1 Details of the PET/CT scans
[11C]mHED baseline | [11C]mHED desipramine | [11C]mHED kinetic modelling | [18F]LMI1195 baseline | [18F]LMI1195 desipramine | |
|---|---|---|---|---|---|
Group size | 5 | 6 | 3 | 6 | 6 |
Body weight (g) | 20.2–23.8 | 19.6–22.9 | 27.5–28.9 | 19.1–24.5 | 20.5–22.8 |
Activity (MBq) | 2.8–11.5 | 3.5–13.9 | 9.2–11.0 | 3.3–10.8 | 1.2–8.6 |
Dose (nmol/kg)a | 9.2.0–61.6 | 9.6–50.0 | 1.5–2.0 | 1.6–18.3 | 3.0–11.8 |
Scan duration (min) | 60 | 60 | 60 | 90 | 90 |
Scan start p.i. (min) | 1 | 1 | − 1 | 1 | 1 |