Fig. 2

Cerebral glucose metabolism and 5-HT_1A receptor availability assessed by [¹⁸F]FDG and [¹⁸F]MPPF μPET. a Average parametric maps of [¹⁸F]MPPF binding potential. b [¹⁸F]MPPF binding in the medial prefrontal cortex, septum, and hippocampus. A significant increase of hippocampal [¹⁸F]MPPF binding became evident in rats with daily transport to the laboratory and a 1-h stay in the laboratory. c Averaged [¹⁸F]FDG metabolic maps. d [¹⁸F]FDG uptake did not significantly differ between groups in any brain region of interest. Data are shown as mean ± SEM. *P < 0.05