Table 1 HPLC analysis results of the native and conjugated 1C1m-Fc
Native 1C1m-Fc | 1C1m-Fc + 10 equivalents DOTA | 1C1m-Fc + 20 equivalents DOTA | 1C1m-Fc + 40 equivalents DOTA | |
|---|---|---|---|---|
% of the main peak | 97.4 | 94.5 | 92.4 | 94.9 |
% of aggregates | 2.12 | 5.3 | 6.7 | 4.6 |
% of other impurities | 0.5 | 0.17 | 0.75 | 0.5 |