Table 5 Absorbed dose of [18F]MC225 for human adults estimated from mouse data
Target organ | Absorbed dose (μGy/MBq) | |
|---|---|---|
With urination* | Without urination | |
Adrenals | 12.9 | 12.9 |
Brain | 5.0 | 5.0 |
Breasts | 7.8 | 7.8 |
Gallbladder | 16.0 | 16.1 |
Lower large intestine wall | 28.9 | 29.7 |
Small intestine | 36.0 | 36.3 |
Stomach wall | 19.5 | 19.5 |
Upper large intestine wall | 30.4 | 30.6 |
Heart wall | 10.3 | 10.3 |
Kidneys | 18.0 | 18.1 |
Liver | 26.9 | 26.9 |
Lungs | 13.4 | 13.4 |
Muscle | 10.2 | 10.4 |
Ovaries | 15.5 | 16.2 |
Pancreas | 63.8 | 63.9 |
Red marrow | 12.0 | 12.2 |
Osteogenic cells | 14.8 | 14.9 |
Skin | 7.1 | 7.1 |
Spleen | 13.9 | 13.9 |
Testes | 8.5 | 9.0 |
Thymus | 9.3 | 9.3 |
Thyroid | 9.2 | 9.2 |
Urinary bladder wall | 32.5 | 59.6 |
Uterus | 15.3 | 17.0 |
Total body | 11.9 | 12.1 |
Effective dose (μSv/MBq) | 15.7 | 16.9 |