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Table 5 Absorbed dose of [18F]MC225 for human adults estimated from mouse data

From: Automated synthesis, preclinical toxicity, and radiation dosimetry of [18F]MC225 for clinical use: a tracer for measuring P-glycoprotein function at the blood-brain barrier

Target organ Absorbed dose (μGy/MBq)
With urination* Without urination
Adrenals 12.9 12.9
Brain 5.0 5.0
Breasts 7.8 7.8
Gallbladder 16.0 16.1
Lower large intestine wall 28.9 29.7
Small intestine 36.0 36.3
Stomach wall 19.5 19.5
Upper large intestine wall 30.4 30.6
Heart wall 10.3 10.3
Kidneys 18.0 18.1
Liver 26.9 26.9
Lungs 13.4 13.4
Muscle 10.2 10.4
Ovaries 15.5 16.2
Pancreas 63.8 63.9
Red marrow 12.0 12.2
Osteogenic cells 14.8 14.9
Skin 7.1 7.1
Spleen 13.9 13.9
Testes 8.5 9.0
Thymus 9.3 9.3
Thyroid 9.2 9.2
Urinary bladder wall 32.5 59.6
Uterus 15.3 17.0
Total body 11.9 12.1
Effective dose (μSv/MBq) 15.7 16.9
  1. *Urination at 360 min after injection