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Table 4 Mean organ radiation doses (mSv/MBq). Adult male and female values were based on the residence times measured in males and females, respectively (n = 2, each). For the adolescent calculation, the 4 residence time values were used, with the exception of reproductive organs

From: Human adult and adolescent biodistribution and dosimetry of the synaptic vesicle glycoprotein 2A radioligand 11C-UCB-J

 

55-kg female

70-kg male

15-year-old adolescents

Mean

+/−

Mean

+/−

Mean

+/−

Adrenals

3.71E03

9.19E05

2.96E03

8.49E05

3.63E03

9.57E05

Brain

2.31E−02

2.83E−04

1.38E−02

7.78E−04

1.87E−02

1.75E−03

Breasts

1.86E03

1.84E04

1.63E03

9.90E05

1.94E03

1.52E04

Gallbladder wall

1.40E−02

2.33E−03

1.03E−02

3.66E−03

1.39E−02

3.37E−03

LLI wall

2.34E−02

8.13E−03

2.06E−02

6.36E−04

2.66E−02

5.84E−03

Small intestine

2.95E03

1.77E04

2.71E03

1.41E05

3.22E03

1.75E04

Stomach wall

6.71E03

4.36E03

6.95E03

4.46E03

7.88E03

4.38E03

ULI wall

3.03E03

8.49E05

2.62E03

2.12E05

3.05E03

1.21E04

Heart wall

4.97E03

6.15E04

3.91E03

1.20E04

5.12E03

4.70E04

Kidneys

1.07E02

3.54E04

9.56E03

1.05E03

1.18E02

8.38E04

Liver

2.48E−02

1.27E−03

1.48E−02

7.78E−04

2.17E−02

3.87E−03

Lungs

6.20E03

3.34E03

4.27E03

4.81E04

6.23E03

2.55E03

Muscle

2.21E03

6.36E05

2.00E03

6.36E05

2.33E03

1.38E04

Ovaries

3.46E03

4.24E04

  

3.53E03

4.17E04

Pancreas

3.91E03

4.67E04

2.83E03

2.97E04

4.12E03

4.23E04

Red marrow

2.39E03

4.95E05

2.05E03

5.66E05

2.46E03

9.25E05

Osteogenic cells

3.40E03

1.98E04

2.81E03

1.41E04

3.47E03

2.46E04

Skin

1.72E03

9.90E05

1.55E03

7.78E05

1.80E03

1.28E04

Spleen

4.69E03

6.36E05

4.50E03

1.70E04

5.50E03

1.81E04

Testes

  

1.92E03

1.41E05

2.40E03

1.41E05

Thymus

2.19E03

2.55E04

1.92E03

1.27E04

2.31E03

2.02E04

Thyroid

1.84E03

1.84E04

1.89E03

1.13E04

2.25E03

1.93E04

Urinary bladder wall

2.18E−02

9.19E−03

2.24E−02

7.00E−03

2.43E−02

8.13E−03

Uterus

3.18E03

3.46E04

  

3.23E03

3.39E04

Total body

3.48E03

4.95E05

2.75E03

4.95E05

3.47E03

5.56E05

Effective dose (mSv/MBq)

8.20E03

1.69E03

6.97E03

8.70E04

8.79E03

1.25E03