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Table 2 Estimated parameters from baseline scan of three baboons using different compartmental models

From: PET imaging of soluble epoxide hydrolase in non-human primate brain with [18F]FNDP

 

2TCM

1TCM

Logan

VT (mL/mL)

K1 (mL/cm3/min)

VT (mL/mL)

K1 (mL/cm3/min)

VT (mL/mL)

Thalamus

7.90 ± 0.74

0.17 ± 0.03

7.42 ± 0.36

0.16 ± 0.03

7.87 ± 0.55

Hypothalamus

8.32 ± 0.57

0.15 ± 0.03

7.77 ± 0.35

0.14 ± 0.03

8.08 ± 0.44

Hippocampus

11.47 ± 2.61

0.15 ± 0.04

10.27 ± 1.55

0.14 ± 0.03

10.97 ± 1.96

Temporal gyrus

9.77 ± 1.02

0.17 ± 0.03

9.05 ± 0.41

0.16 ± 0.03

9.52 ± 0.57

Frontal gyrus

10.50 ± 1.01

0.18 ± 0.04

9.58 ± 0.60

0.16 ± 0.04

10.29 ± 0.91

Corpus callosum

9.28 ± 0.90

0.17 ± 0.03

8.32 ± 0.91

0.15 ± 0.03

9.06 ± 0.99

Globus pallidus

9.74 ± 1.02

0.19 ± 0.03

9.07 ± 0.66

0.17 ± 0.03

9.44 ± 0.92

White matter

9.29 ± 1.08

0.18 ± 0.04

8.43 ± 0.89

0.17 ± 0.04

9.00 ± 1.03

Occipital cortex

7.82 ± 1.82

0.18 ± 0.06

7.39 ± 1.56

0.17 ± 0.06

7.67 ± 1.63

Cerebellum

7.66 ± 0.72

0.19 ± 0.03

7.33 ± 0.45

0.18 ± 0.03

7.63 ± 0.58

Amygdala

12.49 ± 2.47

0.14 ± 0.03

10.51 ± 0.81

0.14 ± 0.03

11.98 ± 1.63

Putamen

13.80 ± 2.27

0.23 ± 0.05

12.87 ± 1.54

0.22 ± 0.05

13.32 ± 1.81

Caudate

13.90 ± 2.28

0.21 ± 0.05

12.95 ± 1.44

0.21 ± 0.05

13.35 ± 1.94

Insula

13.76 ± 1.42

0.22 ± 0.05

12.13 ± 1.08

0.20 ± 0.05

12.82 ± 1.32

AIC

− 38.96 ± 33.09

− 1.65 ± 12.24

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  1. *The results show mean and standard deviation computed from 3 baboons’ parameters.