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Table 3 Univariate analysis of clinicopathological variables for PFS after lanreotide therapy

From: Tumour-to-liver ratio determined by [68Ga]Ga-DOTA-TOC PET/CT as a prognostic factor of lanreotide efficacy for patients with well-differentiated gastroenteropancreatic-neuroendocrine tumours

Variable

Hazard ratio (95% CI)

p value

EGOG performance status (1 vs. 0)

3.749 (1.084–12.965)

0.037*

Primary tumour site (pancreas vs. other)

0.864 (0.0.356–2.097)

0.746

NET WHO grade (2 and 3 vs. 1)

1.833 (0.611–5.499)

0.279

Presence of carcinoid symptoms (yes vs. no)

0.616 (0.203–1.868)

0.392

Previous surgery (yes vs. no)

0.720 (0.290–1.789)

0.480

Previous chemotherapy (yes vs. no)

0.947 (0.217–4.133)

0.942

Lanreotide dose (90 mg vs. 120 mg)

2.030 (0.464–8.888)

0.347

Hepatic tumour volume assessed by CT/MRI (> 25% vs. 0–25%)

0.466 (0.170–1.275)

0.137

  1. CI confidence interval
  2. *Statistically significant (p < 0.05)