Fig. 3

Representative examples of patients with or without glioma recurrence/progression investigated with [¹⁸F]-F-DOPA PET imaging, with axial slices of [¹⁸F]-F-DOPA PET (left column), dynamic TBR_mean curves (middle column) providing the time-to-peak delay-time (light blue dotted line), and the 10-to-30 min slope (dark blue dotted line), along with, for illustrative purposes, the same slice location recorded on a FLAIR MRI sequence (right column). a 51-year-old woman with no recurrent or progressive glioma (TBR_mean = 0.8, TBR_max = 1.1, TSR_mean = 0.5, TSR_max = 0.7, MTV = 0 mL, TTP = 30 min, and slope = 0.31 h⁻¹). b 46-year-old woman with a progressive IDH-wildtype glioblastoma (TBR_mean = 1.9, TBR_max = 2.5, TSR_mean = 1.2, TSR_max = 1.6, MTV = 6.13 mL, TTP = 7.6 min, and slope = − 1.22 h⁻¹)