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Fig. 2 | EJNMMI Research

Fig. 2

From: Targeted beta therapy of prostate cancer with 177Lu-labelled Miltuximab® antibody against glypican-1 (GPC-1)

Fig. 2

Uptake of [177Lu]Lu-DOTA-Miltuximab® in tumour-bearing BALB/c/nude mice. a Imaging of Cerenkov radiation from representative mice bearing DU-145-RFP-Luc xenografts on days 3 and 5 post intravenous injection of 6 MBq [177Lu]Lu-DOTA-Miltuximab®. b, c Biodistribution in %injected activity (IA)/gram and %IA/organ, respectively, of [177Lu]Lu-DOTA-Miltuximab® in tumour-bearing BALB/c/nude mice on day 3 (n = 3), day 5 (n = 2), day 7 (n = 2) and day 27 endpoint (n = 6) post injection of a 6 MBq dose, assessed by gamma counting of organs ex vivo. Shown are mean with SEM

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