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EJNMMI Research
Fig. 5 | EJNMMI Research

Fig. 5

From: Quantification and reliability of [11C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung — a test-retest PET study in control subjects

Fig. 5

Representative parametric lung images obtained from DEPICT analysis of [11C]VC-002 binding in subject #1. Note that the heart and liver were not included in the generation of parametric images. a Fractional blood volume (Vb). b Kinetic rate constant K1, showing the radioligand influx rate from blood to tissue that is proportional to blood flow and the radioligand extraction coefficient. c Total distribution volume (VT), which is the main outcome parameter of the analysis. d Compartmental model order (MO), showing the estimated number of pharmacokinetic compartments in tissue that is sufficient to adequately describe the data

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