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EJNMMI Research
Fig. 3 | EJNMMI Research

Fig. 3

From: Quantification and reliability of [11C]VC - 002 binding to muscarinic acetylcholine receptors in the human lung — a test-retest PET study in control subjects

Fig. 3

a Radiochromatogram from gradient HPLC analysis of human plasma at 30 min after I.V. injection of [11C]VC-002 in subject #1. The larger peak to the right represents unchanged [11C]VC-002, whereas the left peak represents a radioactively labelled metabolite that is more polar than [11C]VC-002. b Time course for the fraction (%) of radioactivity in plasma representing unchanged [11C]VC-002 (mean fitted curves with SD indicated using error bars). An empirical model using the Richards equation [25] was fitted to the measured parent fraction

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