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Table 2 SUVmax and T/N ratio of gliomas

From: Diagnostic value of PET/CT with 11C-methionine (MET) and 18F-fluorothymidine (FLT) in newly diagnosed glioma based on the 2016 WHO classification

Characteristic

MET

FLT

SUVmax, median (IQR)

T/N ratio, median (IQR)

SUVmax, median (IQR)

T/N ratio, median (IQR)

Grade

 II (n = 12)

2.99 (1.94–4.23)

2.51 (1.86–3.13)

0.49 (0.30–0.69)

2.24 (1.69–2.62)

 III (n = 24)

5.92 (4.65–6.52)

5.03 (3.58–6.39)

1.29 (0.90–1.49)

6.25 (4.59–8.69)

 IV (n = 45)

6.21 (4.45–7.66)

5.99 (4.64–7.39)

2.77 (1.92–3.29)

15.24 (11.11–20.49)

IDH status

 Mutant (n = 29)

4.83 (3.04–6.37)

3.6 (2.87–5.59)

0.93 (0.47–1.44)

4.18 (2.28–6.39)

 Wildtype (n = 52)

6.11 (4.63–7.56)

5.91 (4.54–7.35)

2.59 (1.61–3.24)

14.7 (8.98–20.39)

Histology and subtype

 DA (n = 9)

2.77 (1.86–3.69)

2.03 (1.83–2.97)

0.46 (0.23–0.57)

2.35 (1.69–2.60)

  IDH-mut (n = 8)

2.76 (1.75–4.01)

2.45 (1.85–3.26)

0.45 (0.23–0.59)

2.07 (1.69–2.62)

  IDH-wt (n = 1)

2.85

1.83

0.57

2.48

 OD (n = 3)

3.68 (3.31–4.29)

2.86 (2.51–3.23)

0.59 (0.49–0.73)

2.14 (1.91–3.42)

 AA (n = 14)

5.22 (4.06–5.84)

4.65 (3.25–5.99)

1.37 (0.89–1.47)

7.16 (4.77–9.41)

  IDH-mut (n = 6)

4.50 (3.14–5.67)

3.28 (2.99–5.19)

0.99 (0.68–1.35)

4.9 (3.48–6.98)

  IDH-wt (n = 8)

5.76 (5.26–5.83)

5.41 (4.11–6.20)

1.66 (0.90–2.36)

8.1 (6.58–14.53)

 AO (n = 10)

6.91 (5.14–7.79)

5.07 (4.72–7.21)

1.18 (0.97–1.49)

5.82 (4.26–6.79)

 GBM (n = 45)

6.21 (4.45–7.66)

5.99 (4.64–7.39)

2.77 (1.92–3.29)

15.24 (11.11–20.46)

  IDH-mut (n = 2)

5.44 (4.64–6.24)

5.6 (5.59–5.60)

1.90 (1.74–2.06)

14.58 (14.47–14.69)

  IDH-wt (n = 43)

6.25 (4.58–7.71)

6.19 (4.63–7.41)

2.81 (1.95–3.32)

15.65 (10.35–20.77)