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Fig. 6 | EJNMMI Research

Fig. 6

From: Diagnostic value of PET/CT with 11C-methionine (MET) and 18F-fluorothymidine (FLT) in newly diagnosed glioma based on the 2016 WHO classification

Fig. 6

Box plots showing the T/N ratios of MET and FLT in relation to glioma grading in IDH1-mutant tumours (a, b) and in IDH1-wildtype tumours (c, d). In IDH1-mutant tumours, the tracer uptake in grade III gliomas was significantly higher than that in grade II gliomas both in MET-PET (P = 0.002) (a) and FLT-PET (P < 0.001) (b). In IDH1-wildtype tumours, there was no significant difference in the median MET T/N ratios between grade III and IV gliomas (c). The median FLT T/N ratio in grade IV gliomas was significantly higher than that in grade III gliomas (P = 0.029) (d)

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