From: Radiation dosimetry of 18F-AzaFol: A first in-human use of a folate receptor PET tracer
Organ AD in mGy/MBq | ||||||||
---|---|---|---|---|---|---|---|---|
Organs/patient | 1 (F) | 2 (M) | 3 (F) | 4 (M) | 5 (M) | 6 (M) | Average | SD |
Adrenals | 2.61E− 02 | 1.93E− 02 | 2.27E− 02 | 2.00E− 02 | 2.06E− 02 | 2.52E− 02 | 2.23E− 02 | 2.84E− 03 |
Brain | 4.67E− 03 | 3.26E− 03 | 4.80E− 03 | 3.32E− 03 | 3.36E− 03 | 3.27E− 03 | 3.78E− 03 | 7.42E− 04 |
Breasts | 9.68E− 03 | – | 1.01E− 02 | – | – | – | 9.89E− 03 | 2.97E− 04 |
Esophagus | 1.63E− 02 | 1.29E− 02 | 1.45E− 02 | 1.37E− 02 | 1.25E− 02 | 1.37E− 02 | 1.39E− 02 | 1.35E− 03 |
Eyes | 7.77E− 03 | 7.76E− 03 | 9.04E− 03 | 7.58E− 03 | 7.57E− 03 | 7.73E− 03 | 7.91E− 03 | 5.61E− 04 |
Gallbladder wall | 2.33E− 02 | 2.05E− 02 | 1.97E− 02 | 2.15E− 02 | 2.00E− 02 | 2.47E− 02 | 2.16E− 02 | 1.99E− 03 |
Left colon | 2.89E− 02 | 2.45E− 02 | 2.15E− 02 | 2.56E− 02 | 2.46E− 02 | 3.32E− 02 | 2.64E− 02 | 4.10E− 03 |
Small intestine | 3.44E− 02 | 2.54E− 02 | 2.32E− 02 | 2.64E− 02 | 2.53E− 02 | 3.37E− 02 | 2.81E− 02 | 4.76E− 03 |
Stomach wall | 3.05E− 02 | 1.57E− 02 | 2.23E− 02 | 2.19E− 02 | 1.57E− 02 | 2.22E− 02 | 2.14E− 02 | 5.47E− 03 |
Right colon | 3.09E− 02 | 2.62E− 02 | 2.19E− 02 | 2.74E− 02 | 2.60E− 02 | 3.50E− 02 | 2.79E− 02 | 4.52E− 03 |
Rectum | 3.05E− 02 | 2.42E− 02 | 2.39E− 02 | 2.48E− 02 | 2.41E− 02 | 3.06E− 02 | 2.64E− 02 | 3.27E− 03 |
Heart wall | 2.04E− 02 | 1.78E− 02 | 2.06E− 02 | 1.72E− 02 | 1.57E− 02 | 1.78E− 02 | 1.83E− 02 | 1.91E− 03 |
Kidneys | 4.54E− 02 | 3.85E− 02 | 6.01E− 02 | 3.80E− 02 | 4.96E− 02 | 4.31E− 02 | 4.58E− 02 | 8.25E− 03 |
Liver | 8.34E− 02 | 4.08E− 02 | 4.95E− 02 | 4.45E− 02 | 3.92E− 02 | 5.38E− 02 | 5.19E− 02 | 1.64E− 02 |
Lungs | 2.84E− 02 | 2.19E− 02 | 2.19E− 02 | 2.89E− 02 | 2.25E− 02 | 1.77E− 02 | 2.36E− 02 | 4.31E− 03 |
Ovaries | 1.46E− 02 | – | 1.56E− 02 | – | – | – | 1.51E− 02 | 7.07E− 04 |
Pancreas | 2.30E− 02 | 1.55E− 02 | 1.94E− 02 | 1.65E− 02 | 1.53E− 02 | 1.87E− 02 | 1.81E− 02 | 2.94E− 03 |
Prostate | – | 2.98E− 02 | – | 1.30E− 02 | 1.93E− 02 | 1.95E− 02 | 2.04E− 02 | 6.96E− 03 |
Salivary glands | 8.62E− 03 | 9.16E− 03 | 9.91E− 03 | 8.99E− 03 | 8.88E− 03 | 9.13E− 03 | 9.12E− 03 | 4.36E− 04 |
Red marrow | 1.26E− 02 | 1.17E− 02 | 1.47E− 02 | 1.15E− 02 | 1.89E− 02 | 1.23E− 02 | 1.36E− 02 | 2.83E− 03 |
Osteogenic cells | 9.65E− 03 | 9.61E− 03 | 1.11E− 02 | 9.44E− 03 | 1.36E− 02 | 1.01E− 02 | 1.06E− 02 | 1.60E− 03 |
Spleen | 2.56E− 02 | 1.55E− 02 | 2.22E− 02 | 1.58E− 02 | 1.73E− 02 | 1.16E− 01 | 3.54E− 02 | 3.97E− 02 |
Testes | – | 9.50E− 03 | – | 9.20E− 03 | 9.04E− 03 | 9.14E− 03 | 9.22E− 03 | 1.98E− 04 |
Thymus | 1.35E− 02 | 1.16E− 02 | 1.36E− 02 | 1.19E− 02 | 1.11E− 02 | 1.14E− 02 | 1.22E− 02 | 1.09E− 03 |
Thyroid | 9.26E− 03 | 1.28E− 02 | 1.02E− 02 | 1.32E− 02 | 2.56E− 02 | 1.03E− 02 | 1.36E− 02 | 6.10E− 03 |
Urinary bladder wall | 5.54E− 02 | 3.72E− 02 | 6.00E− 02 | 3.34E− 02 | 3.48E− 02 | 1.36E− 02 | 3.91E− 02 | 1.68E− 02 |
Uterus | 1.77E− 02 | – | 1.83E− 02 | – | – | – | 1.80E− 02 | 4.24E− 04 |
Total body | 1.39E− 02 | 1.11E− 02 | 1.37E− 02 | 1.11E− 02 | 1.11E− 02 | 1.16E− 02 | 1.21E− 02 | 1.35E− 03 |
Patient E (wTICRP-103) mSv/MBq | 2.28E− 02 | 1.53E− 02 | 1.91E− 02 | 1.70E− 02 | 1.67E− 02 | 1.73E− 02 | 1.80E− 02 | 2.62E− 03 |
Reference person E (wTICRP-103) mSv/MBq | 2.16E− 02 | 1.82E− 02 | 1.80E− 02 | 2.01E− 02 | 1.98E− 02 | 2.05E− 02 | 1.97E− 02 | 1.38E− 03 |