From: Comparative evaluation of 68Ga-labelled TATEs: the impact of chelators on imaging
%ID/g of organ or tissue | ||||||||
---|---|---|---|---|---|---|---|---|
Organ/tissue | 68Ga-DOTA-TATE | 68Ga-NOTA-TATE | ||||||
15 min | 0.5 h | 1 h | 2 h | 15 min | 0.5 h | 1 h | 2 h | |
Blood | 3.03 ± 1.96 | 1.32 ± 0.39 | 0.35 ± 0.20 | 0.05 ± 0.02 | 3.25 ± 1.06 | 1.01 ± 0.42 | 0.58 ± 0.24 | 0.07 ± 0.06 |
Liver | 1.27 ± 0.77 | 0.61 ± 0.35 | 0.34 ± 0.25 | 0.08 ± 0.07 | 1.19 ± 0.54 | 0.43 ± 0.23 | 0.07 ± 0.04 | 0.04 ± 0.02 |
Spleen | 3.84 ± 4.03 | 1.48 ± 0.84 | 1.92 ± 1.75 | 0.21 ± 0.19 | 0.19 ± 0.08 | 0.13 ± 0.11 | 0.12 ± 0.06 | 0.03 ± 0.01 |
Lungs | 5.10 ± 5.22 | 2.86 ± 1.47 | 4.62 ± 3.42 | 0.98 ± 0.22 | 3.64 ± 1.56 | 0.21 ± 0.17 | 0.64 ± 0.41 | 0.48 ± 0.21 |
Kidney | 10.35 ± 8.89 | 8.12 ± 2.71 | 2.82 ± 2.54 | 1.49 ± 0.57 | 17.1 ± 6.39 | 4.23 ± 2.73 | 3.79 ± 2.16 | 1.69 ± 1.02 |
Gallbladder | 1.47 ± 0.62 | 0.79 ± 0.48 | 0.52 ± 0.31 | 0.11 ± 0.06 | 3.62 ± 1.94 | 6.21 ± 2.69 | 1.83 ± 0.84 | 1.61 ± 0.67 |
Stomach | 4.24 ± 2.66 | 0.98 ± 0.49 | 4.26 ± 2.58 | 0.52 ± 0.39 | 0.19 ± 0.13 | 3.55 ± 1.83 | 1.61 ± 1.03 | 1.11 ± 0.21 |
Intestines | 1.56 ± 1.47 | 1.58 ± 1.77 | 0.91 ± 0.52 | 0.23 ± 0.15 | 0.07 ± 0.04 | 0.03 ± 0.02 | 0.21 ± 0.09 | 0.13 ± 0.07 |
Skeleton | 1.94 ± 0.81 | 1.10 ± 0.63 | 0.80 ± 0.73 | 0.17 ± 0.06 | 2.14 ± 1.41 | 1.46 ± 0.37 | 0.85 ± 0.38 | 0.13 ± 0.07 |
Muscle | 1.18 ± 1.26 | 0.60 ± 0.45 | 0.07 ± 0.02 | 0.04 ± 0.01 | 0.26 ± 0.03 | 0.47 ± 0.26 | 0.08 ± 0.06 | 0.03 ± 0.01 |
Tumour | 3.13 ± 1.75 | 3.62 ± 1.94 | 3.14 ± 2.07 | 2.3 ± 1.34 | 3.24 ± 1.03 | 3.97 ± 2.24 | 3.16 ± 1.92 | 1.33 ± 0.96 |
Tumour/kidney | 0.30 | 0.45 | 1.11 | 1.54 | 0.18 | 0.94 | 0.81 | 0.79 |
T/NT | 2.65 | 6.03 | 44.86 | 57.50 | 12.46 | 8.45 | 39.5 | 44.3 |