Fig. 3

PET measurements of regional time-activity curves for [¹¹C]1 at baseline and in displacement experiments with fenfluramine. a For [¹¹C]1 using fenfluramine at 1.0 mg/kg (i.v.) for displacement. b For [¹¹C]3 using fenfluramine at 1.0 mg/kg (i.v.) for displacement. c For [¹¹C]3 using fenfluramine (5.0 mg/kg, i.v.) for displacement. In all panels, arrows denote injection time of fenfluramine (15 min after radioligand)