Fig. 3
From: PSMA expression level predicts differentiated thyroid cancer aggressiveness and patient outcome
Example of PSMA staining in a 45-year-old female diagnosed with a papillary thyroid cancer (presence of vascular invasion, free surgical margins, pT3mpN1bcM0 – stage I). Panoramic view (a, × 2) shows diffuse PSMA staining which involves endothelial cells almost completely (b, × 20) and was quantified as 90%. Planar images (c) obtained after radioiodine (RAI) treatment (2960 MBq) show uptake in the thyroid bed and in right cervical lymph nodes. At last follow-up (56 months after surgery), the patient was disease free (thyroglobulin 0.2 ng/mL), as also confirmed by diagnostic planar images (d) obtained after RAI administration (185 MBq)