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Table 2 Biodistribution of 152Tb-PSMA-617 in PC-3 PIP/flu tumor-bearing mice

From: Preclinical investigations and first-in-human application of 152Tb-PSMA-617 for PET/CT imaging of prostate cancer

 

152Tb-PSMA-617

177Lu-PSMA-617*

 

1 h p.i.

4 h p.i.

24 h p.i.

1 h p.i.

4 h p.i.

24 h p.i.

Tumor-to-blood

> 200

> 200

> 200

88 ± 16

> 200

> 200

Tumor-to-liver

159 ± 20

179 ± 13

> 200

> 200

> 200

> 200

Tumor-to-kidney

5.7 ± 0.5

19 ± 3

53 ± 19

4.5 ± 0.8

16 ± 3

50 ± 5

  1. *Data obtained from Benešová et al. [16]