Radiation dosimetry of [18F]-PSS232—a PET radioligand for imaging mGlu5 receptors in humans

EJNMMI Research

Table 4 Absorbed organ dose (mGy/MBq) and effective dose (mSv/MBq) using ICRP 30 gastrointestinal model

Organ	Mean	COV	Minimum	Maximum
Adrenals	0.0129	2.3	0.0125	0.0133
Brain	0.0107	10.3	0.0089	0.0121
Breasts	0.0063	17.5	0.0048	0.0080
Gallbladder wall	0.1368	57.5	0.0356	0.2780
Lower large intestine wall	0.0200	14.5	0.0151	0.0250
Small intestine	0.0422	24.2	0.0256	0.0600
Stomach wall	0.0112	3.6	0.0108	0.0117
Upper large intestine wall	0.0473	25.8	0.0274	0.0685
Heart wall	0.0149	8.7	0.0126	0.0166
Kidneys	0.0199	11.6	0.0165	0.0236
Liver	0.0493	20.1	0.0372	0.0648
Lungs	0.0087	8.0	0.0077	0.0099
Muscle	0.0105	9.5	0.0087	0.0117
Ovaries	0.0146	6.2	0.0130	0.0159
Pancreas	0.0183	11.5	0.0162	0.0225
Red marrow	0.0136	5.1	0.0120	0.0143
Osteogenic cells	0.0134	11.2	0.0111	0.0151
Skin	0.0058	13.8	0.0046	0.0069
Spleen	0.0101	14.9	0.0088	0.0132
Testes	0.0071	14.1	0.0055	0.0087
Thymus	0.0120	10.8	0.0103	0.0146
Thyroid	0.0088	6.8	0.0077	0.0096
Urinary bladder wall	0.0185	44.3	0.0137	0.0369
Uterus	0.0134	3.0	0.0128	0.0140
Total body	0.0117	1.7	0.0113	0.0119
Effective dose	0.0150	8.7	0.0131	0.0170