Fig. 2
a Contrast CT image of a liver cancer patient (Pt. 3) with pulmonary and bone metastases displayed lipiodol retention resulted from transarterial embolization and multiple confluent nodular and mass lesions at both lobes of liver. b 188Re-liposome SPECT/CT imaging of tumor targeting and uptake in Pt. 3 at different time points after injection. The patient had previously received transarterial chemoembolization (TACE), which left a region with hyperdense lipoid as well as central necrotic area (white arrow). Several necrotic lesions show hypodense CT image and less radioactivity. Some viable tumor masses were either displayed as solid nodules or formed a rim-like structure surrounding the necrotic regions (red arrows). The radioactivity uptake of normal liver was indicated by yellow arrows