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Table 1 Growth and histology

From: Noninvasive assessment and quantification of tumor vascularization using [18F]FDG-PET/CT and CE-CT in a tumor model with modifiable angiogenesis—an animal experimental prospective cohort study

  H1299 A549 All tumors
Non-co-trans-plantation Co-trans-plantation p value Non-co-trans-plantation Co-trans-plantation p value Non-co-trans-plantation Co-trans-plantation p value
In vivo
 Growth duration Days 49.00 (20) 18.0 (11) < 0.001 45.0 (10) 23.5 (15) < 0.001 45.9 (7) 22.0 (12) < 0.001
In vitro
 Beads Number/FOV 1.10 (0.28) 1.3 (0.17) 0.009 1.1 (0.22) 1.3 (0.23) 0.032 1.1 (0.25) 1.3 (0.22) 0.001
 MVD Number/mm2 89.7 (65.49) 203.1 (185.49) 0.036 114.6 (81.98) 153.4 (112.75) 0.018 101.8 (63.3) 171.4 (120) 0.002
  1. FOV field of view, MVD microvessel density
  2. Tumor growth duration till endpoint and in vitro data derived from histology and immunohistology. Measurements were done as soon the tumors had reached a maximum diameter of 20 mm or after 48 days of growth, depending on which criterion was reached first. First and second column show results separated for both cell lines, third column show results for tumor cell lines merged together. Median (interquartile range)