Fig. 4
From: Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator
Example time-course for radioactivity in lungs and pituitary gland following intravenous injection of [11C]VC-002. The top TACs represent organ radioactivity at baseline and after post-dosing via intravenous infusion of ipratropium (NHP#1, 30 μg/kg). The bottom TACs represent organ radioactivity at baseline and after post-dosing via inhalation of ipratropium (NHP#3, 150 μg/kg)