Comparison of standardized uptake values between 99m Tc-HDP SPECT/CT and 18 F-NaF PET/CT in bone metastases of breast and prostate cancer

EJNMMI Research

Table 3 SUVs_mean,bg from normal appearing bone at different skeletal sites

Skeletal site	PET SUV median (IQR)	SPECT SUV median (IQR)	PET SUV–SPECT SUV median (IQR)^*
Skull	2.6 (2.1–5.0)	2.0 (1.8–2.6)	0.3 (0.1–0.8) (p < 0.01)
Spine	7.4 (6.6–8.7)	6.1 (4.7–6.8)	1.7 (0.6–2.8) (p < 0.001)
Rib cage	3.0 (2.4–4.0)	2.5 (2.0–3.1)	0.7 (−0.1–1.0) (p < 0.001)
Pelvis	5.5 (4.7–6.6)	4.7 (4.1–6.0)	0.6 (−0.2–1.3) (p < 0.01)
Limbs	3.8 (2.9–4.9)	3.2 (2.1–4.3)	0.7 (0.1–1.0) (p < 0.01)

IQR interquartile range
^*p value denotes at which level a median difference is significantly different from 0 according to the Wilcoxon signed rank test