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EJNMMI Research
Fig. 3 | EJNMMI Research

Fig. 3

From: Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 68Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques

Fig. 3

Ex vivo imaging and tracer uptake quantification in the atherosclerotic plaques. Autoradiography (AR) and corresponding Sudan-IV stained aortas excised from ApoE-KO non-blocked, blocked and control mice (a). Whole aorta and plaque surface areas were quantified using Image J software. Quantification of the autoradiography images expressed as intensity per unit area of whole aorta (whole aorta autoradiographic signal/whole aorta area, QL/mm2) (b). Quantification of the autoradiography images expressed as intensity per unit area of plaques ([whole aorta autoradiographic signal − normal aortic tissue autoradiographic signal]/plaque surface area, QL/mm2) (c)

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