18F-FDG and 11C-4DST PET/CT for evaluating response to platinum-based doublet chemotherapy in advanced non-small cell lung cancer: a prospective study

EJNMMI Research

Table 5 Kaplan-Meier estimates and log-rank tests for PFS and OS in FDG and 4DST parameters

Modality	Parameter or interim assessments	p value
Modality	Parameter or interim assessments	PFS	OS
CT	RECIST 1.1	0.79	0.28
FDG	Highest SUV_max	0.63	0.13
	Sum of SUV_max	0.84	0.99
	MTV	0.048	0.02
	TLG	0.12	0.04
	%Δ highest SUV_max	0.07	0.94
	%Δsum of SUV_max	0.46	0.69
	%ΔMTV	0.33	0.78
	%ΔTLG	0.26	0.62
	EORTC	0.53	0.85
	PERCIST	0.78	0.34
4DST	Highest SUV_max	0.56	0.07
	Sum of SUV_max	0.84	0.96
	MTV	0.018	0.007
	TLP	0.53	0.22
	%Δ highest SUV_max	0.45	0.06
	%Δsum of SUV_max	0.58	0.07
	%ΔMTV	0.26	0.29
	%ΔTLP	0.35	0.71

MTV metabolic tumor volume, TLG total lesion glycolysis, TLP total lesion proliferation