Table 4 Results of ROC analysis and PPV, NPV, and accuracy of predicting PFS > 4 months versus PFS ≤ 4 months
Modality | Parameter or interim assessments | AUC | PPV | NPV | Accuracy |
|---|---|---|---|---|---|
CT | RECIST 1.1 | 0.56 | 60.0 | 66.7 | 61.1 |
FDG | Highest SUVmax | 0.51 | 60.0 | 57.1 | 59.1 |
Sum of SUVmax | 0.52 | 41.7 | 30.0 | 36.4 | |
MTV | 0.65 | 77.8 | 61.5 | 68.2 | |
TLG | 0.62 | 66.7 | 53.8 | 59.1 | |
%Δhighest SUVmax | 0.61 | 66.7 | 55.6 | 61.1 | |
%Δsum of SUVmax | 0.53 | 61.5 | 60.0 | 61.1 | |
%ΔMTV | 0.61 | 66.7 | 55.6 | 61.1 | |
%ΔTLG | 0.64 | 66.7 | 66.7 | 66.7 | |
EORTC | 0.60 | 70.0 | 55.6 | 66.7 | |
PERCIST | 0.59 | 61.5 | 60.0 | 72.2 | |
4DST | Highest SUVmax | 0.70 | 80.0 | 66.7 | 72.7 |
Sum of SUVmax | 0.51 | 40.0 | 71.2 | 40.9 | |
MTV | 0.73 | 80.0 | 66.7 | 72.7 | |
TLP | 0.72 | 72.7 | 63.6 | 68.2 | |
%Δhighest SUVmax | 0.64 | 58.3 | 57.1 | 57.9 | |
%Δsum of SUVmax | 0.65 | 70.0 | 66.7 | 68.4 | |
%ΔMTV | 0.59 | 60.0 | 55.6 | 57.9 | |
%ΔTLP | 0.59 | 58.3 | 57.1 | 57.9 |