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Fig. 3 | EJNMMI Research

Fig. 3

From: Preclinical evaluation of PSMA expression in response to androgen receptor blockade for theranostics in prostate cancer

Fig. 3

ARB increases PSMA at the tumor cell surface. Tumor volume of C4-2 (a) tumors was determined by CT (ENZ vs. vehicle, p = 0.05; BIC vs. vehicle, p = 0.02). 68Ga-PSMA11 PET signal (%IAmean/g) in C4-2 (b) tumors (ENZ vs. vehicle, p = 0.02; BIC vs. vehicle, p = n.s.). PSMA mean fluorescent intensity (MFI) is shown for each group (ENZ vs. vehicle, p = 0.03; BIC vs. vehicle, p = n.s.) (c). The fold-change during ARB treatment, related to the pre-treatment volume is shown. Data are shown as mean ± SD. Asterisks indicate significance

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