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Table 4 Tumour-to-normal tissue ratios of 177Lu-SS-03 and 99mTc-SS-04 after 1, 4, and 24 h of administration in nude mice bearing HEK293-rsst2 tumour xenografts

From: The tetraamine chelator outperforms HYNIC in a new technetium-99m-labelled somatostatin receptor 2 antagonist

 

177Lu-SS-03

99mTc-SS-04

1 h

4 h

24 h

1 h

4 h

24 h

Tumour/blood

41.3

150.5

360.9

25.5

218.1

981.3

Tumour/liver

7.9

18.1

55.8

6.6

9.2

17.4

Tumour/kidney

1.56

1.86

3.58

0.95

1.85

5.16

Tumour/muscles

109.5

259.3

372.1

73.6

382.1

616.7

Tumour/bone

5.7

11.5

21.1

14.9

51.3

74.1