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Table 4 Tumour-to-normal tissue ratios of 177Lu-SS-03 and 99mTc-SS-04 after 1, 4, and 24 h of administration in nude mice bearing HEK293-rsst2 tumour xenografts

From: The tetraamine chelator outperforms HYNIC in a new technetium-99m-labelled somatostatin receptor 2 antagonist

  177Lu-SS-03 99mTc-SS-04
1 h 4 h 24 h 1 h 4 h 24 h
Tumour/blood 41.3 150.5 360.9 25.5 218.1 981.3
Tumour/liver 7.9 18.1 55.8 6.6 9.2 17.4
Tumour/kidney 1.56 1.86 3.58 0.95 1.85 5.16
Tumour/muscles 109.5 259.3 372.1 73.6 382.1 616.7
Tumour/bone 5.7 11.5 21.1 14.9 51.3 74.1