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Table 2 Binding affinities (IC50, nM) of chelator-peptide conjugates

From: The tetraamine chelator outperforms HYNIC in a new technetium-99m-labelled somatostatin receptor 2 antagonist

Compound IC50 (nM)*
sst1 sst2 sst3 sst4 sst5
SS-03 > 1000 1.7 ± 0.06 > 1000 404 ± 92 564 ± 174
SS-04 > 1000 5.3 ± 0.17 720 ± 74 171 ± 35 228 ± 73
DOTA-sst2-ANT [22] > 1000 1.5 ± 0.4 > 1000 287 ± 27 > 1000
SS-28 5.2 ± 0.3 2.7 ± 0.38 7.7 ± 0.9 5.6 ± 0.4 4.0 ± 0.3
  1. *Values are IC50 in nM (mean ± SEM; n ≥ 3)