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Table 4 SUVmax measurements in extracardiac sites of increased 18F-florbetaben uptake on delayed images

From: 18F-florbetaben whole-body PET/MRI for evaluation of systemic amyloid deposition

Site of uptake

Patients

SUVmax (mean)

Patients with uptake (%)

Clinical/pathological organs involvement

1

2

3

4

5

6

7

8

9

Bone marrow

3.2a,b

2.4a

3.2a,b

3a

3.4a

3.4a,b

4.7a

3.3

7/9 (77%)

4/9 (44%)

Spleen

2.6a (D)

1.1 (D)

1.2 (D)

1.1 (D)

25.1a (D)

16.7a (D)

8

6/9 (66%)

 

Kidneys

1.6

1.8

1.3

1.9

2.1

1.9

1.9

6.4a

5.9a

2.8

9/9 (100%)

5/9 (55%)

Stomach

3.7a (D)

3.9a (D)

11.9a,b (F)

4.9a (D)

31.2a (D)

5.9a (D)

10.3

6/9 (66%)

2/9 (22%)

Parotids

1.2 (B)

4 (B)

3.4 (B)

9.4a (B)

4.5a (B)

3.5 (B)

1.1 (B)

2.4 (B)

5.3a (B)

3.9

9/9 (100%)

 

Submandibular Glands

2.9 (B)

4.4a (B)

3.7

2/9 (22%)

 

Lungs

2.2a,b (F)

2.7a (D)

2.5

2/9 (22%)

1/9 (11%)

Thyroid

11.5a (B)

5.8a (B)

8.7

2/9 (22%)

 

Orbital muscles

4a,b (B)

2.5a

3.3

2/9 (22%)

 

White matter

2

1.8

2.9a

2.5a

2

2.8a

0.8

2.8a

3.4a

2.3

9/9 (100%)

 

Gray Matter

1

0.9

3.4a

2.9a

1.3

1

0.8

2.6a

1.6

1.7

9/9 (100%)

 

Skeletal Muscles

2.8a (B)

2.2a

4.5a (B)

3.2

3/9 (33%)

 

Tongue

5.8a

2.3

3.3a

6.3a

4.4

4/9 (44%)

1/9 (11%)

Pleura

5.7a (D)

3.7a (D)

4.7

2/9 (22%)

 
  1. D diffuse, B bilateral, F focal
  2. aIncreased uptake above adjacent background was considered abnormal
  3. bPositive MRI:
  4. • bone marrow (patients #1, 4, 8): non-specific heterogeneous T1w marrow signal
  5. • lungs (patient #2): basilar lung consolidation with moderate right and mild left pleural effusions
  6. • stomach (patient #3): area of asymmetric wall thickening and lack of enhancement
  7. • ocular muscles (patient #2): mild predominantly lateral rectus muscle thickening