Table 2 Results of PET/CT imaging (patient-based) and impact on patient’s management
Patient | Pre-PET/CT morphological imaging | 18F-FDG PET/CT | 68Ga-SRI PET/CT | Change in management | Patient management | Follow-up (months) | Outcome | ||
|---|---|---|---|---|---|---|---|---|---|
Type | Result (findings) | Results (findings) | Results (findings) | Expected | Undertaken | ||||
1 | CT | Positive (residual primary MCC, Lns) | TP (residual primary MCC, Lns, liver) | TP (primary MCC, Lns) | Yes | Local RT | CHT | 9 | Dead in PD |
2a | CT | Positive (Lns) | TP (Lns) | TP (Lns) | No | CHT | CHT | 8 | Dead in PD |
3 | CT | Positive/suspicious (lung) | TN | TN | Yes | Individualized treatment | Wait and see | 67 | Alive, NED |
4 | CT | Positive (1 residual Ln) | TP (1 Ln) | TP (1 Ln) | No | Surgery + RT (lymph node) | Surgery + RT (lymph node) | 34 | Dead in PD |
5 | US | Negative | TN | TN | No | Adjuvant RT (loco-regional lymph nodes) | Adjuvant RT (loco-regional lymph nodes) | 54 | Alive, NED |
6 | CT | Positive/suspicious (Lns, liver) | TN | TN | Yes | CHT | Adjuvant RT (loco-regional lymph nodes) | 52 | Alive, NED |
7 | CT, MRI | Positive (residual primary MCC) | TP (residual primary MCC) | TP (primary MCC) | No | CHT | CHT | 43 | Alive, NED |
8 | CT | Positive (Lns) | TP (Lns) | TP (Lns) | Yes | CHT | SS analogs treatment | 8 | Dead in PD |
9 | CT | Negative | FP# (skin) | FP# (skin) | No | Adjuvant RT (primary site + loco-regional lymph nodes) | Adjuvant RT (primary site + loco-regional lymph nodes) | 27 | Alive, NED |
10* | US | Negative | TN | FP§ (liver) | No | Wait and see | Wait and see | 66 | Dead (MCC-unrelated) |
11* | US | Positive/suspicious (Lns) | TP (Lns, skin) | TP (Lns, skin) | No | CHT | CHT | 21 | Dead in PD |
12 | CT, US | Negative | TN | TN | No | Wait and see | Wait and see | 122 | Alive, NED |
13 | CT, US | Negative | TN | TN | No | Wait and see | Wait and see | 118 | Alive, NED |
14* | US | Positive (Lns) | TP (Lns, thoracic wall, adrenals) | TP (Lns, thoracic wall, adrenals) | No | CHT | CHT | 7 | Dead in PD |
15* | CT | Positive (Lns) | TP (Lns) | TP (Lns) | No | CHT | CHT | 9 | Dead in PD |