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Table 1 Body, liver weight, and blood parameters in mice fed a CDAHFD

From: Evaluation of hepatic integrin αvβ3 expression in non-alcoholic steatohepatitis (NASH) model mouse by 18F-FPP-RGD2 PET

Parameter Control 3 weeks CDAHFD 3 weeks Control 8 weeks CDAHFD 8 weeks
Body weight (g) 24.44 ± 0.91 20.81 ± 0.96** 26.41 ± 1.56 21.66 ± 2.23**
Liver weight (g) 1.11 ± 0.11 1.47 ± 0.17** 1.12 ± 0.13 1.69 ± 0.24**
AST (IU/L) 32.80 ± 3.83 436.6 ± 76.35** 41.20 ± 12.69 402.70 ± 242.78**
ALT (IU/L) 19.20 ± 3.45 772.10 ± 128.63** 31.90 ± 16.52 584.6 ± 475.74**
TG (mg/dL) 155.7 ± 48.57 41.50 ± 17.69** 146.80 ± 65.67 21.50 ± 3.54**
TC (mg/dL) 80.40 ± 7.91 49.00 ± 6.95** 79.70 ± 9.50 36.3 ± 4.14**
  1. Statistical differences were assessed using Steel-Dwass test
  2. AST aspartate transaminase, ALT alanine aminotransferase, TC total cholesterol, TG, triglyceride
  3. **p < 0.01 compared with respective control mice