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Table 1 Body, liver weight, and blood parameters in mice fed a CDAHFD

From: Evaluation of hepatic integrin αvβ3 expression in non-alcoholic steatohepatitis (NASH) model mouse by 18F-FPP-RGD2 PET

Parameter

Control 3 weeks

CDAHFD 3 weeks

Control 8 weeks

CDAHFD 8 weeks

Body weight (g)

24.44 ± 0.91

20.81 ± 0.96**

26.41 ± 1.56

21.66 ± 2.23**

Liver weight (g)

1.11 ± 0.11

1.47 ± 0.17**

1.12 ± 0.13

1.69 ± 0.24**

AST (IU/L)

32.80 ± 3.83

436.6 ± 76.35**

41.20 ± 12.69

402.70 ± 242.78**

ALT (IU/L)

19.20 ± 3.45

772.10 ± 128.63**

31.90 ± 16.52

584.6 ± 475.74**

TG (mg/dL)

155.7 ± 48.57

41.50 ± 17.69**

146.80 ± 65.67

21.50 ± 3.54**

TC (mg/dL)

80.40 ± 7.91

49.00 ± 6.95**

79.70 ± 9.50

36.3 ± 4.14**

  1. Statistical differences were assessed using Steel-Dwass test
  2. AST aspartate transaminase, ALT alanine aminotransferase, TC total cholesterol, TG, triglyceride
  3. **p < 0.01 compared with respective control mice