Impact of time-of-flight PET on quantification accuracy and lesion detection in simultaneous 18F-choline PET/MRI for prostate cancer

EJNMMI Research

Table 1 MRI protocol parameters

	Axial LAVA-FLEX^a	Coronal T2w FRFSE-XL^b	Axial T2w FRFSE-XL (Pelvic)	Coronal T2w FRFSE-XL (Pelvic)	Axial DWI^c EPI^d (Focus) (Pelvic)
Repetition time, TR (ms)	5618	6326	2600	2900	4000
Echo time, TE (ms)	2.66	118	118	121	67.2
Flip angle, FA (degrees)	12	111	125	125	90
Acquisition matrix	344 × 256	288 × 224	416 × 224	416 × 224	160 × 80
Image size (voxels)	512 × 512	512 × 512	512 × 512	512 × 512	256 × 256
Reconstruction diameter (mm)	460	480	180	200	240
Slice thickness (mm)	3 (3D)	5	4	4	4
Signal averages	0.68	1	4	4	–
b-values (s/mm2) and signal averages	–	–	–	–	0 (6 av.)
					400 (8 av.)
					700 (16 av.)
Diffusion direction	–	–	–	–	‘All’
Bandwidth (Hz/pixel)	651	355	326	326	1953
Acquisition time (mm:ss)	0:18	0:52	3:39	4:04	5:16

^a3D, fast spoiled gradient echo imaging technique that generates water only, fat only, in phase, and out of phase echoes in one single acquisition (GE Healthcare, Waukesha, WI, USA)
^bFast relaxation fast spin echo
^cDiffusion-weighted imaging
^dEcho-planar imaging