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Fig. 4 | EJNMMI Research

Fig. 4

From: In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model

Fig. 4

PET images and TACs of [11C]1 or [18F]2 in MDA-MB-231 tumour bearing SCID mice (n = 4 per group). Tumours are indicated with white dotted ellipses, background tissue (muscle) is indicated with a red arrow. a Representative PET images of [18F]FDG scan and the last time-frame (40–60 min) after administration of [11C]1 under baseline and blocking conditions, and TACs of tumour under baseline (blue line) and blocking (red line) conditions and of background tissue under baseline (green line) and blocking (yellow line) conditions. b Representative PET images of [18F]FDG scan and the last time-frame (40–60 min) under baseline conditions, and after blocking (ERW1041E) and self-blocking with 2 after administration of [18F]2, together with TACs of tumour under baseline (blue line) and blocking conditions (red and purple line), and of background tissue under baseline (green line) conditions

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