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Table 3 Blood pressure, kidney function and catecholamines

From: Renal sympathetic nerve activity after catheter-based renal denervation

  PRE-RDN POST-RDN p value
Parameters
Blood pressure
 Office based systolic (mmHg) 172.0 [162.0–185.0] 153.0 [140.0–178.0] 0.036
 Office based diastolic (mmHg) 97 [90.5–112.5] 90.0 [81.5–100.5] 0.531
 ABPM daytime systolic (mmHg) 166.0 [157.0–179.5] 165.0 [141.5–186.0] 0.578
 ABPM daytime diastolic (mmHg) 98.0 [87.0–108.0] 93.0 [83.0–99.5] 0.409
 ABPM night time systolic (mmHg) 151.0 [133.5–158.5] 145.0 [125.0–165.5] 0.490
 ABPM night time diastolic (mmHg) 84.0 [75.5–90.0] 80.0 [71.0–91.5] 0.640
 ABPM average systolic (mmHg) 160.0 [150.5–173.0] 157.0 [138.5–174.0] 0.602
 ABPM average diastolic (mmHg) 93.0 [83.5–100.5] 92.0 [80.0–94.5] 0.369
Antihypertensive drugs
 Number of antihypertensive drugs 4.6 ± 1.3 4.4 ± 1.4 0.157
 3 classes, n (%) 5 (23.8) 7 (33.3)  
 4 or more classes, n (%) 16 (76.2) 14 (66.7)  
Kidney function
 Creatinine serum (μmol/L) 94.0 [76.5–107.5] 89.0[73.5–113.5] 0.369
 eGFR (ml/min/1.73 m2) 60.7[48.5–101.9] 64.6 [48.0–99.9] 0.218
 Proteinuria (g/L/24 h) 0.10 [0.07–0.20] 0.11 [0.07–0.26] 0.722
 Sodium urine (mmol/24 h) 161 [102–203] 128 [90–161] 0.230
(Neuro) endocrine activity
 Plasma renin activity (μg/A1/L/h) 1.70 [0.95–3.20] 1.0 [0.60–1.68] 0.409
 Epinephrine supine, plasma (nmol/L) 0.12 [0.05–0.23] 0.10 [0.05–0.17] 0.780
 Norepinephrine supine, plasma (nmol/L) 2.43 [1.32–3.78] 2.76 [1.49–4.02] 0.324
 Epinephrine urine (nmol/24 h) 27.5 [14.5–33.8] 26.0 [18.0–38.0] 0.551
 Norepinephrine urine (nmol/24 h) 268.5 [137.5–495.0] 308.5 [237.5–479.3] 0.245
 Metanephrine urine (nmol/24 h) 0.78 [0.49–1.05] 0.68 [0.50–1.02] 0.506
 Normetanephrine urine (nmol/24 h) 2.13 [1.73–3.37] 2.53 [1.74–3.02] 0.911