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Table 3 Comparison of 18F-FDG PET/MRI parameters according to head and neck cancer treatment failure after surgery

From: Prognostic value of simultaneous 18F-FDG PET/MRI using a combination of metabolo-volumetric parameters and apparent diffusion coefficient in treated head and neck cancer

18F-FDG PET/MRI parameters Treatment failure (n = 22) No evidence of disease (n = 50) P value
PET parameters
 SUVmax 9.7 ± 3.9 9.7 ± 5.0 0.582
 MTV 13.5 ± 13.3 7.5 ± 7.9 0.049*
 TLG 71.8 ± 81.5 40.2 ± 52.6 0.057
MRI parameters
 ADCmean 827.3 ± 232.7 972.1 ± 365.1 0.074
Combined PET/MRI parameters
 (SUVmax/ADCmean) × 1000 12.8 ± 6.0 11.3 ± 6.7 0.208
 (MTV/ADCmean) × 1000 17.8 ± 20.1 7.6 ± 7.3 0.018*
 (TLG/ADCmean) × 1000 91.1 ± 102.9 40.0 ± 48.6 0.025*
  1. SUVmax maximum standardized uptake value, MTV metabolic tumor volume, TLG total lesion glycolysis, ADCmean mean apparent diffusion coefficient
  2. *Statistically significant (P < 0.05)