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Table 3 Local residual tumor based on MRI (radiologist), PET (nuclear physician), and PET-MRI (consensus radiologist and nuclear physician) scores and change of opinion and policy

From: Positron emission tomography-magnetic resonance imaging (PET-MRI) for response assessment after radiation therapy of cervical carcinoma: a pilot study

Patient

MRI local

PET local

MRI-PET local

Change of opinion (reason)

Policy of change

1

TN

TN

TN

2

TN

TN

TN

3

TN

Equivocal

TN

+ PET artifact

+ Follow-up

4

FP

FP

Equivocal

+ No PET uptake at suspicious MRI lesion

+ Additional imaging

5

FN

TP

FN

+ FDG uptake artifact at PET-MR

− Metastasis

6

TP

TP

TP

7

FP

TN

Equivocal

+ Consensus + MRI, non-suspicious PET

+ Additional imaging

8

Equivocal

TN

FP

+ Consensus PET-MR, PET hard to interpret due to low-FDG glucose uptake

+ Salvage surgery

9

Equivocal

TP

TP

+ MR partial volume, clear FDG uptake

+ Salvage surgery

10

TN

FP

TN

+ PET hotspot outside cervical tissue

− Metastasis

  1. Abbreviation: TN true negative, TP true positive, FP false positive, FN false negative, + positive, − negative