Table 1 Estimated mean difference and Bland-Altman limits of agreement for the paired differences of measurements
Number of interim analyses | Estimated mean difference and Bland-Altman limits of agreement at analysis time point | |||
|---|---|---|---|---|
Interim analysis 1 | Interim analysis 2 | Interim analysis 3 | Final analysis | |
0 | – | – | – | 0.30 –1.78 to 2.38 (N = 45) |
1 | 0.47 –2.30 to 3.24 (N = 23) | – | – | 0.30 –1.78 to 2.38 (N = 45) |
2 | 0.25 –1.53 to 2.03 (N = 15) | 0.43 –2.03 to 2.89 (N = 30) | – | 0.30 –1.78 to 2.38 (N = 45) |
3 | 0.19 –1.85 to 2.24 (N = 11) | 0.47 –2.30 to 3.24 (N = 23) | 0.40 –1.92 to 2.73 (N = 34) | 0.30 –1.78 to 2.38 (N = 45) |