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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: Motor impairment and compensation in a hemiparkinsonian rat model: correlation between dopamine depletion severity, cerebral metabolism and gait patterns

Fig. 1

[18F]FDOPA imaging in 6-OHDA- and sham-injected rats. a Horizontal view of average [18F]FDOPA images over n = 6 sham (a) and n = 7 6-OHDA-injected rats (b). Images with injections on the right side were flipped so that all injections are displayed on the left. The white circle shows the location of the implanted guide cannula for the stimulation electrode (electrode was not inserted in this study). The black circle shows the 6-OHDA or saline injection site. Horizontal and transverse section planes are indicated in the upper right corner. VOIs are shown below. c Mean [18F]FDOPA SUVRcer values (with standard deviation) from the VOIs displayed in the insert. Asterisks: significant differences (paired t test, p < 0.05) between ipsi- and contralesional VOIs. Abbreviations: c contralesional, core core of nucleus accumbens, i ipsilesional, lat.sh. lateral shell of nucleus accumbens, lStr lateral striatum, med.sh. medial shell of nucleus accumbens, mStr medial striatum, Str striatum, SUVRcer standardised uptake value ratio with cerebellum as reference

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