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Table 3 Comparison of diagnostic accuracy for recurrence by tumor volume-corrected cutoff values

From: Optimization of diagnostic performance for differentiation of recurrence from radiation necrosis in patients with metastatic brain tumors using tumor volume-corrected 11C-methionine uptake

  Sensitivity (%) Specificity (%) PPV (%) NPV (%) Accuracy (%)
Non-corrected cutoff value (1.61) 70.6 80.8 83.7 61.8 74.0
MTV-corrected cutoff value 78.4 80.8 88.9 65.6 79.2
  1. PPV positive predictive value, NPV negative predictive value, MTV metabolic tumor volume, MTV-corrected optimal cutoff value MTV ≤ 0.5 cm3—cutoff 1.23, 0.5 < MTV ≤ 4 cm3—cutoff 1.54, MTV > 4 cm3—cutoff 1.85